Heterogeneity of benign prostatic hyperplasia
نویسندگان
چکیده
Background. Benign prostatic hyperplasia (BPH) is a histologically determined condition of the male body and characterized by glandular-stromal multi-focal proliferation originating from paraurethral (or) transition zone prostate gland. Proliferative processes in are under control immune system. Identifying understanding immunological aspects can help tissue growth, improving men's quality life. The aim our study was to conduct pilot study, assessment status patients with benign hyperplasia. Materials methods. included having stage 2 BPH (according Guyon’s updated classification system (n=8)) who did not have clinical morphological manifestations BPH. subjects underwent standard examinations accordance protocol Ministry Health Republic Belarus. immunogram indicators included: main subpopulations lymphocytes (CD3 T lymphocytes, CD4 helper cells, CD8 cytotoxic lymphocytes), ratio Th/Tc, CD19 B level serum immunoglobulins IgG, IgM, IgA circulating immunocomplexes (CIC), as well phagocytic index number. Results. Patients had statistically lower levels number phagocytosed units compared without Furthermore, highly variable results for indices. Thus, Th/Tc ranged 1,3 2,3 units, CIC – 10 more than 300 units. variability obtained allowed us divide into two groups: first group (n=3) normal indices Th/Tc; second (n=5) that significantly exceeded reference values. None concomitant autoimmune disease. Conclusions. dysfunction Even such small enrolled subjects, it possible form subtypes they future phenotypes. aiming at finding disorders should be continued.
منابع مشابه
Benign prostatic hyperplasia.
This article reviews the epidemiology of benign prostatic hyperplasia (BPH), evaluation of patients with lower urinary tract symptomatology (LUTS), and management of patients with BPH and LUTS. The evaluation includes history and physical examination, laboratory testing, and specialized studies. The management includes medical and surgical options. Medical options include alpha-1-adrenergic rec...
متن کاملBenign Prostatic Hyperplasia
Urinary obstruction as a result of benign prostatic disease has probably been recognized to some degree since the earl iest days of medicine. This association was probably f irst formalized by Riolan in the seventeenth century. In the mideighteenth century, Morgagni (248) provided one of the earl iest descriptions of BPH and enumerated many of the potential medical problems attendant to its dev...
متن کاملBenign Prostatic Hyperplasia (bph)
Comprehensive studies show that the holmium laser is ideal for treating BPH. Holmium laser treatments have been the most rigorously investigated BPH techniques. Over 90 articles have been published from 8 randomized clinical trials and over 30 case studies and comparative series. The American, European, British and Australasian urology associations recommend holmium laser for BPH treatment. Hol...
متن کاملBenign prostatic hyperplasia
Benign prostatic hyperplasia (BPH; Pic. 1) is characterized by increased size of the prostate leading to difficulties with passing the urine. The cells of prostate may increase in numbers (hyperplasia) or in size (hypertrophy) resulting in larger size of prostate. As result, prostatic nodules form in the transition zone of the prostate, which is the area where the prostate is surrounding the ur...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Immunopatologiâ, allergologiâ, infektologiâ
سال: 2022
ISSN: ['2412-320X']
DOI: https://doi.org/10.14427/jipai.2022.2.45